Quinolines and derivatives
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Filtered Search Results
eMolecules 303085-53-2 | 6-Chloropyridazine-3-carbaldehyde | Ambeed | MFCD10698041 | 142.540 | C5H3ClN2O | 95.000 | Clc1ccc(C=O)nn1 | 1g | 528956450
6-Chloropyridazine-3-carbaldehyde | Ambeed | 303085-53-2 | MFCD10698041 | 142.540 | C5H3ClN2O | 95.000 | Clc1ccc(C=O)nn1 | 1g | 528956450
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eMolecules 5622-36-6 | METHYL 2-(QUINOLIN-6-YL)ACETATE | AstaTech | MFCD04038669 | 201.225 | C12H11NO2 | 95.000 | COC(=O)Cc1ccc2ncccc2c1 | 25g | 392628210
METHYL 2-(QUINOLIN-6-YL)ACETATE | AstaTech | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 95.000 | COC(=O)Cc1ccc2ncccc2c1 | 25g | 392628210
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eMolecules 58794-09-5 | 7-bromoisoquinoline | Pharmablock | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 10g | 551259465
7-bromoisoquinoline | Pharmablock | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 10g | 551259465
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Medchemexpress LLC Selenocystamine dih 25g
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Selenocystamine dihydrochloride is a selenocysteine derivative that can be used in the synthesis of other active compounds Selenocystamine dihydrochloride can also induce the aggregation of amphiphilic p-sulfonatocalixarene to form supramolecular nanoparticles[1][2][3]
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Medchemexpress LLC Azido-PEG9-amine | 1207714-69-9 | MFCD30723241 | 98.5% | 482.57 g/mol | C20H42N4O9 | 100 MG
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Azido-PEG9-amine is an azide-terminated nine-unit polyethylene glycol (PEG) linker with a terminal primary amine used for bioconjugation and linker design. It is suitable for click chemistry and linker-based constructs, providing hydrophilic spacing between functional groups.
- Azide-terminated PEG linker compatible with CuAAC and SPAAC click reactions.
- Contains a primary amine for orthogonal functionalization.
- Nine ethylene glycol units provide hydrophilicity and spacing for conjugates.
- Reported high purity supports conjugation and analytical workflows.
- Available in small research-scale quantities for method development.
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Medchemexpress LLC M-PEG12-amine | 1977493-48-3 | MFCD00131599 | ≥98.0% | 559.69 g/mol | C25H53NO12 | 100 MG
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m-PEG12-amine is a methoxy-terminated polyethylene glycol linker containing a 12-unit PEG chain and a terminal primary amine. It serves as a flexible, non-cleavable spacer for conjugation chemistry in linker and ADC/PROTAC synthesis.
- Methoxy-terminated PEG chain, 12 units.
- Terminal primary amine suitable for amide or carbamate coupling.
- Molecular weight approximately 559.7 g/mol; formula C25H53NO12.
- High purity (≥98%) appropriate for research and synthesis workflows.
- Supplied in small-scale quantities suitable for laboratory use.
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Medchemexpress LLC TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | MFCD31657341 | 99.7% | 432.39 | C22H27Cl2N5 | 10 MG
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TLR7/8 agonist 1 dihydrochloride is a small-molecule imidazoquinoline research compound that acts as a dual agonist of Toll-like receptors 7 and 8. It is intended for use in immunology and inflammation studies and demonstrates low-nanomolar activity in receptor assays, suitable for both in vitro and in vivo experimental applications.
- Dual agonist of TLR7 and TLR8 with low-nanomolar potency.
- High reported purity (99.7%).
- Molecular weight 432.39 and formula C22H27Cl2N5.
- High solubility in DMSO (83.33 mg/mL) and compatible with common in vivo vehicles.
- Supplied as an off-white to light yellow solid and available as a DMSO solution.
- Storage: 4°C sealed; in solvent store at -80°C for long term.
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eMolecules 59483-84-0 | Bis(perfluorophenyl) carbonate | ChemScene | MFCD00368353 | 394.124 | C13F10O3 | 98.000 | Fc1c(F)c(F)c(OC(=O)Oc2c(F)c(F)c(F)c(F)c2F)c(F)c1F | 25g | 632313539
Bis(perfluorophenyl) carbonate | ChemScene | 59483-84-0 | MFCD00368353 | 394.124 | C13F10O3 | 98.000 | Fc1c(F)c(F)c(OC(=O)Oc2c(F)c(F)c(F)c(F)c2F)c(F)c1F | 25g | 632313539
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eMolecules 59107-51-6 | 8-chloronaphthalen-1-amine | Synthonix | MFCD00465087 | 177.630 | C10H8ClN | 97.000 | Nc1cccc2cccc(Cl)c12 | 25g | 808551854
8-chloronaphthalen-1-amine | Synthonix | 59107-51-6 | MFCD00465087 | 177.630 | C10H8ClN | 97.000 | Nc1cccc2cccc(Cl)c12 | 25g | 808551854
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Medchemexpress LLC LM11A-31 50mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 50 MG
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LM11A-31 is a small-molecule, non-peptide ligand of the p75 neurotrophin receptor (p75NTR) that acts as a proNGF antagonist. It is brain-penetrant and has been shown to block p75-mediated cell death and to reverse cholinergic neurite dystrophy in preclinical Alzheimer's disease models, and is supplied for research use.
- Non-peptide p75 neurotrophin receptor ligand
- Acts as a proNGF antagonist and blocks p75-mediated cell death
- Brain-penetrant and orally active in preclinical models
- Documented activity in Alzheimer's disease models
- Provided with analytical documentation such as COA, H-NMR, and LC-MS
- High reported purity for research applications
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Medchemexpress LLC B7-H2/ICOSLG protein, cynomolgus | >95.0% | 20 UG
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B7-H2/ICOSLG protein (cynomolgus) is a recombinant extracellular domain of the ICOS ligand produced in HEK293 mammalian cells with a C-terminal His tag. Supplied lyophilized from PBS (pH 7.4), the protein is intended for immunology and receptor-ligand interaction studies and is characterized by low endotoxin and a defined amino acid range (M1-T256).
- Recombinant protein expressed in HEK293 mammalian cells.
- C-terminal His tag for purification and detection.
- Amino acid range M1-T256 corresponding to the extracellular domain.
- Observed molecular weight 50-70 kDa.
- Endotoxin <1 EU/μg (LAL method).
- Lyophilized formulation from PBS, pH 7.4; recommend aliquoting for storage.
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Medchemexpress LLC N-(6-aminohexyl)maleimide trifluoroacetate | 731862-92-3 | MFCD11519191 | 99.7% | 310.27 g/mol | C12H17F3N2O4 | 500 MG
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Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker supplied as the trifluoroacetate salt for research use. It contains a maleimide reactive terminus and a six-carbon amino linker that enables conjugation to thiols and amines, supporting synthesis of targeted protein degraders and other bioconjugates. The material is provided as a high-purity solid with recommended sealed storage to maintain stability.
- Alkyl chain linker with maleimide and amino functional groups.
- Trifluoroacetate salt form for improved handling and stability.
- High reported purity suitable for synthetic applications.
- Compatible with common solvents such as DMSO for reaction setup.
- Intended for research use in PROTAC and bioconjugation workflows.
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Medchemexpress LLC 7-bromoquinoline-4-carboxylic acid | 31009-04-8 | MFCD11108751 | 96.1% | 252.06 | C10H6BrNO2 | 500 MG
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7-Bromoquinoline-4-carboxylic acid is an organic small-molecule reagent used primarily as an intermediate in synthetic chemistry and for biochemical assay research. It is a brominated quinoline carboxylic acid commonly employed to build substituted heterocycles and as a starting material for structure-activity studies.
- Used as an intermediate in chemical synthesis and biochemical research.
- Molecular formula C10H6BrNO2 and molecular weight 252.06 g·mol-1.
- CAS number 31009-04-8 for unambiguous identification.
- Typical purity 96.1% (HPLC) as reported on the certificate of analysis.
- Appearance: gray to brown solid.
- Recommended storage: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC SARS-CoV-2-IN-86 | 368866-07-3 | MFCD02683117 | 99.4% | 466.53 | C26H30N2O6 | 1 G
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SARS-CoV-2-IN-86 is a small-molecule research compound that inhibits SARS-CoV-2 methyltransferases (nsp14 and nsp16) and is reported as an andrographolide derivative. It is supplied as a solid or as a 10 mM solution in DMSO for in vitro antiviral and enzymatic studies. Batch-specific certificates of analysis and safety documentation are available from the supplier.
- Inhibits SARS-CoV-2 methyltransferases (nsp14 and nsp16).
- Andrographolide derivative for antiviral research.
- Available as solid and 10 mM solution in DMSO.
- High purity (≈99.4%) per supplier documentation.
- Suitable for in vitro enzymatic and antiviral assays.
- Powder stable at -20°C; solvent storage guidelines available.
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Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | 103285-22-9 | MFCD00274123 | 98.0% | 560.59 | C31H32N2O8 | 5 G
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine is a DMT-protected uridine analog used as a nucleoside building block and intermediate for the synthesis of modified oligonucleotides. It is supplied as a light-yellow solid with defined purity and storage specifications suited for research and preparative oligonucleotide chemistry.
- DMT protected at the 5' hydroxyl for selective chain assembly.
- 2'-O-methyl modification supports increased nuclease resistance in oligonucleotides.
- High purity material suitable for synthesis and analytical workflows.
- Available in gram-scale pack sizes to accommodate different synthesis scales.
- Stable under recommended storage conditions to preserve quality over time.
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